glp-1 glucose Receptor Agonists – Peripheral Brain GLP-1: Actions on Beta-cell Mass
Description
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Abstract Glucagon-like peptide-1 receptor agonist (GLP-1RA), a novel hypoglycemic agent for the treatment of type 2 diabetes, has well-known effects such as lowering blood sugar, ameliorating inflammation, reducing weight, and lowering blood lipids
To address this problem and to gain market advantage, pharmaceutical companies have developed various combination therapy products for type 2 diabetes
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They block the proton pumps in stomach lining cells that produce acid, reducing acid output by up to 90%
Eng received a patent for exendin-4 in 1996
