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CMS Issues Coverage Guidance on GLP-1 Anti-Obesity Drugs: Implications for Health Plans Posted on April 5, 2024 CMS Issued Coverage Guidance on GLP-1 Anti-Obesity Drugs Requiring Considerations for Health Plans GLP-1s (glucagon-like peptide 1 agonist) came up in the news again after the Centers for Medicare and Medicaid Services (CMS) issued coverage guidance on GLP-1 anti-obesity drugs with expanded indications on March 20, 2024.* Since the inception of Medicare Part D, drugs used for weight loss have been excluded from basic coverage

Wegovy belongs to a class of medications called GLP-1 (glucagon-like peptide-1) receptor agonists, more commonly known as GLP-1s

Proposed mechanisms are depicted in Figure 2

Future research should examine changes in body weight among patients who are fully adherent to GLP-1 agonist therapy and identify factors associated with less observed weight loss in real world patients living with diabetes

Neuroprotective Effect of Liraglutide in an Experimental Mouse Model of Multiple Sclerosis: Role of AMPK/SIRT1 Signaling and NLRP3 Inflammasome

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