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Common side effects of GLP-1RAs, including semaglutide, involve gastrointestinal reactions such as nausea and vomiting

Bipolar disorder and diabetes mellitus: evidence for disease-modifying effects and treatment implications
Other Approaches May Be Better If You: Have insurance coverage for FDA-approved GLP-1s

Hypoglycemia is a significant concern in diabetic patients undergoing surgery, especially during the preoperative period if surgery is delayed after the patient has received a morning injection of intermediate-acting insulin

When you excrete excess water, you lose sodium, potassium, and magnesium along with it
Key supplements for anyone on GLP-1 therapy include a high-quality multivitamin, vitamin B12 (especially important since some compounded formulations include B12 for this reason), vitamin D, and a fiber supplement if constipation is an issue