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The cost-effectiveness analysis yielded an incremental cost-effectiveness ratio (ICER) of 22,691 per QALY gained for the base case target population at the 10-year horizon, below the Italian WTP threshold, Table 1

Phase 3 TRIUMPH trial results The Phase 3 TRIUMPH-4 trial, announced in late 2025, confirmed and even improved on the Phase 2 numbers

We have successfully established ourselves in the International market.

Several participants expressed a desire for increased availability of the medication to other people, and were aware that the funding was only for a limited period

PLoS ONE 11 , e0165224 (2016)

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