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PKA also activates cAMP response element-binding protein (CREB), which can, in turn, drive cell growth by stimulating PDX-1 via insulin receptor substrate 2 (Irs2) signalling [17,31]

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We initialize both the number and centroid of clusters using a density-based clustering algorithm called Hierarchical Density-Based Spatial Clustering of Applications with Noise (HDBSCAN) first and fine-tune the assignment of discussions into the appropriate topics using KMeans clustering

Originally published June 12, 2024