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Strong observational results can open the door to new clinical questions, but trial data will need to confirm if semaglutide truly has a direct therapeutic effect on depression, anxiety, addiction-related harm, or suicidality

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GLP-1 RAs are a class of synthetic peptides designed to mimic the actions of this endogenous hormone, but with a longer duration of action

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While some patients experienced temporary blurred vision or minor visual disturbances that resolved without permanent damage, NAION represents a fundamentally different and far more serious condition