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The company estimates that more than 50% of patients taking GLP-1 drugs stop because of costs, while more than a third do so because of side effects

10.1001/jamanetworkopen.2024.16775 [DOI] [PMC free article] [PubMed] [Google Scholar] 58

GLP-1 stimulates the -cells to produce Insulin, blocks pancreatic -cells' glucagon release via somatostatin (96), slows down gastric emptying (131), improves peripheral glucose tolerance (132), suppresses appetite in the hypothalamus and amygdala (97), increases -cell mass, GSIS, and elicits protection from glucolipotoxicity (133) and apoptosis (134)

Understanding your genetic profile helps your provider anticipate potential digestive challenges and personalize your treatment plan, including dose timing or meal composition guidance tailored to your peptide genetics

PMCID: PMC12922244

Due to the compelling findings of antagonistic properties, GIP(7-30)NH 2 was named ANTGIP (60)