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Electrolyte supplementation and adequate sleep dramatically reduce the severity of this adaptation period
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Study participants reported a median body mass index (BMI) of 35.1 kg m 2 before initiating GLP1 treatment, with 96.8% of participants having a BMI of at least 25 at baseline

Liraglutide once daily, dulaglutide once weekly, and subcutaneous semaglutide once weekly have all demonstrated superior cardiovascular outcomes compared with placebo when added to standard-of-care treatment in patients with type 2 diabetes who had a history of cardiovascular disease or are at high cardiovascular risk (2426)

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