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Teneligliptin possesses a rigid, Jshaped conformation composed of five rings, four of which directly interact with the DPP4 enzyme, contributing to its exceptionally strong binding compared with other gliptins

What was once a relatively contained therapeutic class within endocrinology has expanded into a dual-purpose platform that operates across two distinct clinical domains

It is important to distinguish between theoretical concerns, findings from animal studies, and actual evidence in human populations

[DOI] [PubMed] [Google Scholar] 613.Baggio L.L., Yusta B., Mulvihill E.E., Cao X., Streutker C.J., Butany J