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doi: 10.3389/fendo.2023.1085799 [DOI] [PMC free article] [PubMed] [Google Scholar] 25.Nauck MA, DAlessio DA

What makes these medications conceptually coherent, beyond the individual findings, is that they fit naturally with a view of addiction as a disorder of dysregulated reward, stress, and self-regulation

Off-label or experimental use of any medication carries inherent risks that must be carefully weighed against potential benefits

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How Retatrutide Starting Dose Compares to Other Medications Compared to medications like semaglutide or tirzepatide, retatrutide is often started cautiously because of its multi-hormone activity

The first 30 amino residues of exendin-4 have 53% sequence homology to mammalian GLP-1, whereas the C-terminal nonapeptide extension has no similarities