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(2) major adverse cardiovascular events (MACE)

In general, look for a powder with at least 20 grams of protein per serving, little to no added sugar, third-party testing and no sugar alcohols, which can worsen gastrointestinal side effects in some people

Mazza highlights that compounded drugs, while not subjected to the same extensive testing as commercial drugs, are essential when shortages arise or specific patient needs must be met

doi: 10.4049/jimmunol.1103801
While these observations are supportive of GLP-1RA use in liver cirrhosis, prospective studies are needed to confirm this

Anyone researching retatrutide should factor this into their risk assessment alongside the standard peptide safety considerations
