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Preventing excessive muscle loss during GLP-1RA therapy ultimately requires a multimodal strategy

This finding complements results from an earlier study that revealed a role for Y1-R agonism in facilitating trans-differentiation of -cells into -cells 21

Riediger, T., Rauch, M

Obesity-related chronic inflammation contributes not only to the alteration of cardiac metabolism, but also to the accumulation of epicardial adipose tissue, which can aggravate the hemodynamic profile and worsen cardiac function
