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In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity

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It's designed for people who have already reached their goals on semaglutide and want to maintain their results, and for anyone who prefers a gentler approach with milder side effects

Retention of glucagon function is required to achieve such an advantage over GLP-1 monotherapy

Learn about side effects, dosage, and more.

Baseline cohort characteristics and treatment effects on initiation of semaglutide 0.5 mg and 1 mg, dulaglutide 1.5 mg and sitagliptin 100 mg were based on the once-weekly semaglutide clinical trial program (SUSTAIN 7 and 2)