down side of semaglutide How Ozempic Affects Your Body: Short & Long-Term Effects Semaglutide Side Effects: Expert Tips
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Managing side effects often requires dose adjustments or careful meal planning, which can add complexity to the treatment experience

Precautions and Considerations Certain individuals should avoid Semaglutide, including those with a history of medullary thyroid cancer, untreated depression, decreased kidney function, or pancreatic disease

The situation is therefore similar to patients taking hypoglycaemic drugs: the high efficacy of the KD may necessitate adjusting (lowering) the dosage of antihypertensive drugs or weaning them off altogether, if clinically indicated
The SmPC specifically advises that the dose of insulin or sulphonylureas may need to be reduced when initiating semaglutide treatment

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