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PI3K/mTOR Axis Mediates GLP-1R Signalling Actions on Glucose Metabolism GLP-1 can regulate cell size, function and proliferation in -cells via PI3K/mTOR pathway 25, 26

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The exact retatrutide dosage depends on the clinical protocol, with treatment typically starting at a lower dose before progressing according to the planned retatrutide dosing schedule under medical supervision

This study aims to provide insights into the effect of GLP1 therapy on mortality and clinical outcomes in patients with cirrhosis