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This gives us a clue that there might be a connection, but randomized controlled studies would be the best way to discover whether semaglutide can actually help people quit smoking. The side effects of semaglutide are well understood and include: abdominal pain constipation diarrhea nausea and vomiting These could deter some people from using this drug to quit smoking

In contrast, switching among patients with an active supply of AOM semaglutide declined slightly from June to July 2025 (1.9%) compared to an average switching rate of 2.3% from January to April

When done correctly, intermittent fasting primarily works for weight loss by helping regulate overall daily calorie intake
This leads to reduced hunger, increased feelings of fullness, and consequently decreased caloric consumption
10.1056/nejmoa2107519 10 FriasJ

In obese people GLP-1 secretion is impaired which might explain why the hunger pangs are constantly active in these people
