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Description
Side effects may include nausea, vomiting, diarrhea, and abdominal discomfort, which typically diminish with time

10.1038/s41419-023-06251-8 91 LvD.FengP.GuanX.LiuZ.LiD.XueC.et al (2024)

However, their higher cost and gastrointestinal side effects may limit accessibility and long-term adherence

You can buy berberine, protein powder, multivitamins, and probiotics independently for $50-80 monthly, getting similar or identical ingredients without the proprietary delivery systems
In clinical trials, many participants experienced substantial losses roughly 15% of initial body weight on average over a 68-week course of treatment

Gutirrez, J