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More concerning but less common side effects include gallbladder problems , potential thyroid issues (a black box warning exists for medullary thyroid carcinoma risk in animal studies), and hair loss related to rapid weight loss rather than the medication itself

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Medicare Part D rarely covers GLP-1 for weight loss alone, while commercial insurers increasingly approve coverage for patients with BMI 30 and documented failed diet attempts or weight-related comorbidities

Weight loss drugs have been available since the 1930s, but their popularity surged recently after the Food and Drug Administration (FDA) approved three GLP-1 receptor agonists for weight loss: Wegovy (semaglutide), Saxenda (liraglutide), and Ozempic (tirzepatide)