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Xultophy is a combination of insulin and liraglutide and is used for treatment of type 2 diabetes

Baseline markers may include: Fasting glucose HbA1c Lipid panels Body composition measurements when available Without baseline measurements, it becomes difficult to determine whether metabolic changes are occurring or whether dose adjustments are producing meaningful effects

Waist circumference is a reliable indicator of abdominal obesity, and it is considered a risk factor for ASCVD independent of body mass index [91]

In individuals without diabetes, sensations of bloating/fullness are more closely associated with emptying from the distal stomach and antral area as measured by ultrasound (50)

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The initial dosing regimen of dulaglutide is 0.75 mg subcutaneously weekly, with the dose increased to 4.5 mg, usually one month after the previous dose