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#ObesityTherapeutics #GLP1 #TernsPharma #ObesityTreatment #ClinicalTrials #MetabolicHealth Terns Pharmaceuticals Halts Obesity Program After Underwhelming Phase 2 Data for Oral GLP-1 (TERN-601) Terns Pharmaceuticals announced topline 12-week Phase 2 FALCON results for its once-daily oral GLP-1 receptor agonist TERN-601 in adults with obesity (BMI 2750 kg/m, without diabetes), showing modest placebo-adjusted weight loss of 4.6%, below internal efficacy targets
Understanding these mechanisms helps distinguish between expected physiological changes and symptoms requiring clinical assessment

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For patients with BMI 35 kg/m (regardless of comorbidities) or BMI 30-34.9 kg/m with metabolic disease, bariatric surgery consultation may be appropriate, according to 2022 American Society for Metabolic and Bariatric Surgery guidelines

Mounjaro (tirzepatide) represents an exciting advancement in obesity treatment offering hope of significant weight loss to those who have struggled with traditional methods alone

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