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3 These agents have also been shown to lower levels of circulating proinflammatory cytokines such as TNF- and IL-6, both implicated in HS pathogenesis, as well as C-reactive protein (CRP), a marker of systemic inflammation that correlates with disease severity

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"That might be seen as being kind of selfish, because those people quite understandably want to lose some weight, but the drug is not tested or designed to help people in that position." He says mixing and injecting weight loss drugs at home comes with "huge risks"

The injectable formulations are administered once weekly via subcutaneous injection, meaning the medication is delivered into the fatty tissue layer beneath the skin rather than into muscle or directly into the bloodstream

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