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Description
NLRP3 inflammasome activation-mediated pyroptosis aggravates myocardial ischemia/reperfusion injury in diabetic rats

And this has been studies in animal data, as well as some recent human data as well

10.1007/s00401-012-1009-1 120
Seven subjects were studied twice at an interval of 9.9 (2.0) days (Supplemental Fig
P.PiresM

Some solid cancers also exhibited high level of GPX4 expression including melanoma, gastric, endometrial, prostate and colorectal cancers
