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This helps clinicians determine how closely to follow patients after GLP-1 RA initiation as they may be at increased short-term risk

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doi: 10.1083/jcb.200205091

The combination of GLP-1 receptor agonists and DPP-4 inhibitors is not recommended, not due to safety issues, but since a clinically significant additional benefit is not expected (see below) (7072)

For sexual function specifically, the testosterone reduction in PCOS women is actually a net positive because it brings abnormally high levels back toward normal range
Nutritional deficiencies from restricted food intakeparticularly low B vitamins, iron, or amino acids needed for neurotransmitter synthesiscan independently trigger or worsen depression
