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However, the sensors and mediators are similar, produced by resident CNS glia (microglia and astrocytes), endothelial cells, and peripherally derived immune cells [179], causing different brain alterations

[DOI] [PMC free article] [PubMed] [Google Scholar] 425.Egecioglu, E., Engel, J

Their finding marked a decisive breakthrough because it challenged a long-standing belief that nerves controlled the secretion of digestive enzymes that had grown out of the work of Ivan Pavlov, the Russian physiologist who demonstrated that dogs can be conditioned to salivate by the sound of a bell (Rehfeld 2012)

Happy to be wrong here

Lots of water

Down 9 lbs in 4 weeks and still going strong