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Conversely, unchanged eating patterns or sedentary behaviour may blunt the weight loss response, though glycaemic benefits generally persist

Official Interaction Data The good news, according to current comprehensive drug interaction databases, is that there are no known direct interactions found between melatonin and Wegovy (semaglutide)

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I would frame these findings as hypothesis-generating and clinically important, but not definitive proof that GLP-1 therapy directly caused the reductions we observed, Sheer says