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De Paepe, M., Leclerc, M., Tinsley, C
For optimal effect, combine with a high-protein, high-fiber diet and regular physical activity
Patients should be reassured that gastrointestinal symptoms often improve with continued therapy as tolerance develops
Further, a few GLP-1 agonists can also help in the treatment of obesity and related heart disease (cardiovascular disease)
Mechanistic hypotheses include reduced leptin-driven T-helper (Th)1/Th17 activity, improved adipokine balance, and modulation of gut-thyroid axis pathways
