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Exposures Two cohorts were assembled, with the first composed of patients who started and continued on GLP-1 receptor agonists or DPP-4 inhibitors between 1 January 2007 and 31 December 2020 and the second composed of patients who started and continued on GLP-1 receptor agonists or SGLT-2 inhibitors between 1 January 1 2013 and 31 December 2020

Demand for these three GLP-1 brands, across their various brands and formulations, has led to unprecedented levels of media attention and unsolicited celebrity endorsements that has resulted in unexpected and intermittent supply shortages

A 54-year-old woman says she ended up at the hospital after taking a popular weight loss drug