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Dual-Agonists (e.g., Tirzepatide): These mimic two hormones, GLP-1 and GIP
With ongoing food intake, anorectic signals overcome the orexigenic tone to terminate feeding
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Using traditional genetic techniques, preclinical studies allow us to determine whether a gene is necessary for surgical outcomes
doi: 10.1016/j.chembiol.2013.01.013
