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Variants associated with stronger GLP-1 receptor activity or faster metabolic clearance may influence how aggressively your prescriber adjusts co-medications like sulfonylureas or blood-pressure drugs

Specifically, the conversion of T4 to the active T3 hormone can slow during caloric deficit, reducing metabolic rate further

^up to 6 weeks from diagnosis

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And there are now some interesting observational data

Any observed reductions in alcohol consumption while taking GLP-1 medications should be discussed with healthcare providers, and comprehensive addiction treatment should remain the standard of care