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The results, published in top-tier journals including the New England Journal of Medicine and Nature Medicine, established tirzepatide as the most effective weight loss peptide available

Eating smaller, more frequent meals, avoiding high-fat or spicy foods, and taking the injection at a time that minimises symptom impact can help

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Serious but rare adverse effects include: Acute pancreatitis (patients should be advised to seek immediate medical attention for severe, persistent abdominal pain) Gallbladder disease, including cholecystitis and cholelithiasis Acute kidney injury, particularly in the context of dehydration from gastrointestinal side effects Hypoglycaemia, especially when used alongside other glucose-lowering medications Thyroid C-cell tumours (observed in rodent studies

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Diabetic Retinopathy Complications in Patients with a History of Diabetic Retinopathy: Rapid improvement of glucose control has been associated with temporary worsening of diabetic retinopathy