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KEGG pathway enrichment analysis further revealed that the differential proteins were primarily involved in key pathways such as retinol metabolism, steroid hormone biosynthesis, PPAR signalling pathway, lysosome, and fatty acid degradation, all of which are closely related to lipid metabolism and protein degradation (Fig

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Setting intermediate milestones, every 25 pounds, every pants size, every health marker improvement, prevents the discouragement that comes from only measuring against a distant final goal

Weight loss is consistent and significant