semaglutide not working yet taking away cravings : r/SemaglutideCompound We don't have a semaglutide
Description
Bottom line You dont just want to lose weightyou want to lose fat while keeping muscle
GLP-1 Mechanism and Clinical Evidence for Weight Loss Semaglutide and other GLP-1 receptor agonists work by mimicking glucagon-like peptide-1, a hormone that regulates appetite and blood glucose

GLP-1 receptors are found throughout the body, including inside the brain, where they are connected to pathways involving reward, stress and impulse control

Declarations Ethics approval and consent to participate This article is based on open-label data and does not contain any new studies conducted by authors on human participants or animals and does not require ethical approval

A thoughtful clinician might argue against switching in one specific scenario: patients with a strong family history of medullary thyroid carcinoma or MEN2 syndrome

Updated May 10, 2024
