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Mesenteric vasoconstriction and hindquarters vasodilatation accompany the pressor actions of exendin-4 in conscious rats

Only a small minority, fewer than 10%, say usage of GLP-1s is viewed positively

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Yet, increased receptor engagement and potential CNS penetrance may amplify neuropsychiatric risk in susceptible individuals

Type 2 diabetes (34.80%) and weight loss (14.71%) emerged as the most predominant indications, while others accounted for 3.92%, and unknown or missing constituted 46.57% (Table 1)

[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Pfeffer M.A., Claggett B., Diaz R., Dickstein K., Gerstein H.C., Kober L.V