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Alsalim W et al

The side effect pattern continues with a few days of increased nausea after the first 10 mg dose, then improvement

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Like all drugs in this class, they carry a boxed warning on the US label that they should not be used in persons with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 because of a signal in rodents that these medications have a dose- and duration-dependent risk of thyroid C-cell tumors [18, 19]