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Although these mechanisms have been exploited to facilitate weight loss, these medications have also been indicated for patients with cardiovascular or renal diseases, all of which have caused a recent drastic rise in prescribing GLP-1 RAs

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Over the last two years, the surging demand for GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) has Over the last two years, the surging demand for GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) has created both clinical and supply chain challenges.

James Januzzi, MD Although our primary endpoint fell short of statistical significance, there are encouraging signals in these results that increase enthusiasm to further evaluate effects of AT-001 on diabetic cardiomyopathy, saidJames Januzzi, MD, Hutter Family Professor of Medicine atHarvard Medical School, a cardiologist atMassachusetts General Hospital, director of Heart Failure Trials at theBaim Institute for Clinical Researchand the studys lead author

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For people comparing basal insulin, Basaglar generic name means insulin glargine and helps clarify brand names, alternatives, safety, and device issues.