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Promotes weight loss by mimicking a GLP-1 hormone

GLP-1 receptor agonists and dual GLP-1/GIP co-agonists can produce substantial weight loss, but caloric restriction and weight loss trigger adaptive thermogenesis ...

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Pancreatic receptors enhance insulin release and improving blood glucose regulation after meals

This suggests that the GLP-1R KO mouse model may serve as a model for correlated metabolic and functional connectivity loss.