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Biguanides exert antitumoral actions in pituitary tumor cells through AMPK-dependent and -independent mechanisms

These effects are greater than those seen with older weight loss medications (typically ~5% total weight loss) and close to typical weight loss seen with bariatric surgery

Aroda et al., 2023)

Kiel DW, Dodson EA, Artal R, Boehmer TK, Leet TL

Personalized GLP-1 Dosing for Colitis Patients PlexusDx offers compounded semaglutide injections starting at $149 per month, with no flat per-compound pricing changes

True GLP-1 agonists (semaglutide, tirzepatide) are prescription medications that directly bind the GLP-1 receptor