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For type 2 diabetes , NICE NG28 recommends continuing GLP-1 treatment only if there is adequate response, defined as HbA1c reduction of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight at 6 months

How GLP-1 Medications Work GLP-1 receptor agonists, such as Semaglutide and Tirzepatide, mimic a natural hormone that helps regulate blood sugar and appetite

Both treatments improved cardiometabolic risk factors, with gastrointestinal side effects being the most common but generally tolerable

It is primarily used to help control blood sugar levels in adults with type 2 diabetes

Patients should be advised to report any new or worsening visual symptoms promptly and attend regular eye screening

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