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Legal Framework Federal Regulations: Ryan Haight Online Pharmacy Consumer Protection Act: Regulates online prescribing and dispensing Requires valid prescription for all prescription medications GLP-1 medications are NOT controlled substances, making telehealth prescribing straightforward Establishes standards for legitimate online medical practice COVID-19 Expanded Telehealth Access: Temporary measures made permanent in many states Expanded what can be prescribed via telemedicine Reduced barriers to virtual care Improved interstate practice for some providers DEA Regulations: While GLP-1s arent controlled, DEA oversees: Pharmacy registrations Telemedicine prescribing standards Interstate medication dispensing State Regulations: Each State Has Different Rules: Provider licensing requirements What can be prescribed via telehealth Whether video/phone consultation required (vs

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Discussion In this nationwide register study, we investigated the association between new users of GLP-1 RAs, SGLT-2 inhibitor users and DPP-4 inhibitor users and the risk of suicide or suicide attempts