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GLP-1-based therapies led to favorable changes in body composition, with significant reductions in VAT and FBM, particularly during the first six months

Effects on weight In the SURPASS programme, change in weight was a prespecified secondary outcome

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Vector construction Previously described expression vectors (pcDNA3.1) encoding human albumin variants (WT, LX, and QMP) were utilized 11,48,60

At the same time, the body burns fewer calories while resting

Additionally, the drugs effects on systemic inflammation and vascular endothelial function may create conditions favoring ischemic events in the posterior ciliary arteries supplying the optic nerve