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Bariatric surgery--which seeks to reduce the size of the stomach or bypass part of the GI tract--was conceived in the 1960s when surgeons observed that gastric cancer patients who had part of the stomach removed (subtotal gastrectomy) went on to lose weight

doi: 10.1016/j.npep.2018.07.003

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Certain Historical Drugs: Individuals who have taken growth hormone from human pituitary glands or bovine insulin from the United Kingdom are permanently deferred due to historical links to Creutzfeldt-Jakob disease

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Semaglutide has years of safety information