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a 2026 analysis of seven trials put the average lean-mass loss around 1.74 kilograms, though as a share of a now-smaller body, lean mass actually rises (Laverde, International Journal of Obesity, 2026)

Areas covered: Literature was searched with no limits on date or language, using various combinations of keywords

They may refer to it as an investigational drug or one thats still undergoing clinical research. Those that do mention the lack of FDA approval tend to do so in tiny print at the bottom of a product page

GLP-1, released in response to food intake, signals the brain to reduce appetite and increase satiety

For additional context on Shed's platform structure and pricing, see our detailed analysis of Shed's GLP-1 program

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