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The cardiovascular benefits of GLP-1 RAs are further supported by considerable preclinical and clinical research, which show that these agents exert favourable modulatory effects on atherosclerosis itself and its risk factors [10]

Although GLP-1RA stimulate sympathetic outflow to adipose tissues in rodents [[68], [69], [70]], a consistent effect on energy expenditure has not been clearly established [78]

Additionally, GLP-1 signalling in the prefrontal cortex may hypothetically enhance cognitive control and decision-making processes, potentially helping individuals resist urges to drink, though this mechanism is primarily supported by animal models rather than human data

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Significant weight loss, improved metabolic health markers, and an overall improvement in quality of life have been reported by patients who have undertaken this treatment