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B12 supplementation is common among GLP-1 users, and many compounded formulations now include B12 in the blend or tirzepatide with B12

[DOI] [PubMed] [Google Scholar] 160.Sun T., Xu W., Wang J., Wang T., Wang S., Liu K., Liu J

As with GLP-1 medications for weight loss, Wegovy for heart disease should be paired with a balanced reduced calorie diet and increased physical activity

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Given that GIP is thought to be important for lipogenesis, the mechanism for this effect of the dual agonist is unclear

[DOI] [PMC free article] [PubMed] [Google Scholar] 298.Kim D.D., Hwang J.H., Fendrick A.M