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Die Aktivierung des GLP-1-Rezeptors resultiert in einer Stimulation der Adenylylcyclase (AC), die ATP in cAMP umwandelt

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Osmotic vs stimulant laxatives (OTC options) First-line pharmacologic option: Polyethylene glycol (PEG 3350) is recommended by gastroenterology guidelines because it increases stool water content, improves stool frequency, and is generally well tolerated for ongoing use. Alternative osmotic option: Magnesium oxide may help some patients and is conditionally recommended in gastroenterology society guidance

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Glucagon-Like Peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets