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Glucagon is traditionally known for raising blood sugar, but in this specific tri-agonist configuration, sustained glucagon receptor activation drives thermogenesis (energy expenditure) and promotes lipid oxidation in the liver

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If these symptoms develop or worsen while on semaglutide despite weight loss, thats inconsistent with GLP-1 effects and warrants endocrine evaluation

Body Mass Index Please note these injection pens can only be prescribed to patients with a (Body Mass Index) BMI of over 30 or over 27.5 plus other risk factors at a doctors discretion such as high blood pressure, colesterol etc * Patients without diabetes and with BMI 30, or BMI 27 plus a weight-related condition, lost an average of 15% of their body weight in 1 year, when paired with healthy lifestyle changes (compared to 2.4% with diet and exercise alone)

Because semaglutide can increase the chance of dehydration, this effect on urine is very common