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As GLP-1 medications can produce significant and sustained weight loss, improvements in body weight and metabolic health likely play a role in the observed risk reduction

IU values assume 10mg/mL vial concentration, where 1 mL equals 100 IU on a standard U-100 insulin syringe

Supplementary material The Supplementary Material for this article can be found online at: Supplementary Figure 1 Threshold for GLP-1R-positivity in flow cytometry

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This obstruction triggers an inflammatory response in the gallbladder wall, which can cause acute cholecystitis, characterized by severe pain, fever, and tenderness in the right upper abdomen