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Accordingly, studies in rodents have demonstrated the ventral tegmental area and nucleus accumbens mediate the effects of GLP-1RAs on alcohol intake 11,12,55

Also report symptoms of gallbladder disease (pain in the right upper abdomen, fever, jaundice), signs of acute kidney injury (decreased urination, swelling, dizziness), vision changes that could indicate diabetic retinopathy complications, or symptoms of thyroid tumors (neck mass, difficulty swallowing, hoarseness)

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These studies have shown adverse effects, including fetal growth restrictions and birth defects, when the medication was administered to pregnant animals