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[DOI] [PubMed] [Google Scholar] 873.Driessen J.H., Henry R.M., van Onzenoort H.A., Lalmohamed A., Burden A.M., Prieto-Alhambra D
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Subgroup analyses indicated reduced risks of colorectal cancer (HR 0.81: 95% CI: 0.680.96) and liver cancer (HR: 0.74

There are also concerns regarding potential drug-interactions and a reduction in long-term efficacy due to tachyphylaxis [73]
