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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Taylor V., MacQueen G

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Producing these molecules at commercial volumes using traditional solid-phase peptide synthesis (SPPS) involves sequential coupling of each amino acid onto a resin-bound support, one step at a time, 31 or 39 times respectively, across reactor volumes measured in the tens of thousands of litres

Lower maintenance doses help prevent rebound while reducing drug exposure